Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14949553 | 0.90 | GAA (0.50) | ALDH1A1MAPK1LMNAKMT2AMEN1 | |
| SCHEMBL9949514 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL9949518 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL3402785 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPK1LMNAKMT2AMEN1 | |
| SCHEMBL3399181 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MAPK1LMNAKMT2AMEN1 | |
| SCHEMBL3397338 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL3425272 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL67753 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL3400610 | 0.80 | GAA (0.57) | KMT2AMEN1KDM4E | |
| SCHEMBL20698377 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |