Serotonin

Serotonin

SCHEMBL1495

NCCc1c[nH]c2ccc(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 1.00
HTR2A P28223 7/20 1.00
HTR1A P08908 7/20 1.00
HTR1D P28221 6/20 1.00
HTR1B P28222 4/20 1.00
HTR7 P34969 3/20 1.00
HTR2B P41595 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP1A2 P05177 2/20 1.00
TSHR P16473 2/20 1.00
HTR5A P47898 2/20 1.00
HTR6 P50406 2/20 1.00
HTR3E A5X5Y0 1/20 1.00
HTR3B O95264 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C9 P11712 1/20 1.00
DRD1 P21728 1/20 1.00
HTR1E P28566 1/20 1.00
HTR1F P30939 1/20 1.00
DRD3 P35462 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serotonin SCHEMBL183226 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL30057954 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29349412 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL8208967 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29781387 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL25341783 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29669289 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL396997 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL3091827 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL1675866 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 205143 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146967-A1 DEVICE AND SENSOR FOR DETECTION OF AN ANALYTE REMINDED, INC. (US) 2026-05-28 US claimed
US-20260144765-A1 COMPOUNDS AND COMBINATIONS THEREOF FOR TREATING NEUROLOGICAL AND PSYCHIATRIC CONDITIONS ANTECIP BIOVENTURES II LLC (US) 2026-05-28 US claimed
US-20260144749-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PICKERING'S OIL-IN-WATER EMULSION CONTAINING AN ORGANOMODIFIED PHYLLOSILICATE, PARTICULARLY FOR ITS USE AS AN ANTI-INFLAMMATORY AND ANTI-ALLERGY AGENT EPHYLA (FR) 2026-05-28 US claimed
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-05-28 US claimed
US-20260144804-A1 USE OF HYOCHOLIC ACID (HCA) SPECIES IN PREPARATION OF MEDICAMENT FOR TREATMENT OF IRRITABLE BOWEL SYNDROME WITH DIARRHEA Centre for Chinese Herbal Medicine Drug Development Limited (HK) 2026-05-28 US claimed
US-20260145003-A1 OCULAR PHOTO-BIO-STIMULATION NeuroRays, LLC (US) 2026-05-28 US claimed
US-20260144773-A1 METHODS OF REDUCING PHYSICAL DEPENDENCE TO NEUROPSYCHIATRIC TREATMENTS SUMITOMO PHARMA AMERICA, INC. (US) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4747247-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF Apogee Pharmaceuticals, Inc. (CA) 2026-05-27 EP claimed
US-12637443-B2 Cyclic amine derivatives having serotonin receptor binding activity SHIONOGI & CO., LTD. (JP) 2026-05-26 US claimed
EP-0005058-A2 Composition for regulating dopamine or norepinephrine levels in neuronal synapses MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1979-10-31 EP claimed
US-4148903-A Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines MERCK & CO., INC. (US) 1979-04-10 US claimed
EP-0000716-A2 Pyrrolo(2,1-b)(3)benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1979-02-21 EP claimed
US-4104398-A 3-Lower alkoxycyproheptadines as serotonin inhibitors MERCK & CO., INC. (US) 1978-08-01 US claimed
US-4098901-A TRIFLUOROMETHYL SUBSTITUTED COMPOUNDS HAVING ANTIDEPRESSIVE ACTIVITY ASTRA LAKEMEDEL AKTIEBOLAG (SE) 1978-07-04 US claimed
US-4073941-A Aralkyl amides having antidepressive activity ASTRA LAKEMEDEL AKTIEBOLAG (SW) 1978-02-14 US claimed
US-4042329-A Method and device for detecting cholesterol BECTON, DICKINSON AND COMPANY (US) 1977-08-16 US claimed
US-4025645-A ETHYL OCTADECADIENOATE9,12- JELENKO III CARL 1977-05-24 US claimed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed