Serotonin

Serotonin

SCHEMBL183226

NCCc1c[nH]c2ccc(O)cc12.NCCc1c[nH]c2ccc(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 1.00
HTR2A P28223 7/20 1.00
HTR1A P08908 7/20 1.00
HTR1D P28221 6/20 1.00
HTR1B P28222 4/20 1.00
HTR7 P34969 3/20 1.00
HTR2B P41595 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP1A2 P05177 2/20 1.00
TSHR P16473 2/20 1.00
HTR5A P47898 2/20 1.00
HTR6 P50406 2/20 1.00
HTR3E A5X5Y0 1/20 1.00
HTR3B O95264 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C9 P11712 1/20 1.00
DRD1 P21728 1/20 1.00
HTR1E P28566 1/20 1.00
HTR1F P30939 1/20 1.00
DRD3 P35462 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serotonin SCHEMBL30057954 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL1495 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29349412 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL8208967 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29781387 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL25341783 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29669289 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL396997 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL3091827 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL1675866 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234708-A Formulations of nudity alkali analogs and methods of use 赛本爱尔兰有限公司 2024-06-21 CN claimed
CN-118064317-A Lactobacillus paracasei for improving cathartic colon and application thereof 江南大学 2024-05-24 CN claimed
CN-117915901-A Combined administration method of deutetrabenazine and CYP2D6 inhibitor 纽罗克里生物科学有限公司 2024-04-19 CN claimed
CN-117479938-A Methods of administering certain VMAT2 inhibitors 纽罗克里生物科学有限公司 2024-01-30 CN claimed
CN-117177959-A Nudity analogs, salts, compositions, and methods of use 赛本爱尔兰有限公司 2023-12-05 CN claimed
CN-117143766-A Lactobacillus paracasei for repairing enteric nerves and application thereof 江南大学 2023-12-01 CN claimed
CN-117024397-A Amphetamine derivatives, preparation method and application thereof 江苏恩华药业股份有限公司 2023-11-10 CN claimed
WO-2023178111-A2 ORGANIC COMPOUNDS INTRA-CELLULAR THERAPIES, INC. (US) 2023-09-21 WO claimed
CN-116438169-A Serotonin receptor modulators 东北大学 2023-07-14 CN claimed
WO-2023133573-A1 METHODS AND SYSTEMS FOR TREATING CHRONIC PAIN CONDITIONS USING DIGITAL THERAPEUTICS IN COMBINATION WITH OTHER THERAPIES Mahana Therapeutics, Inc. (US) 2023-07-13 WO claimed
CN-1653025-A NK1Antagonists SCHERING CORP (US) 2005-08-10 CN claimed
CN-1585748-A NK1 antagonists SCHERING CORP (US) 2005-02-23 CN claimed
CN-1315830-A Method for treating anxiety disorders LILLY CO ELI (US) 2001-10-03 CN claimed
CN-1312802-A Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents AMERICAN HOME PROD (US) 2001-09-12 CN claimed
US-6060642-A TRANSGENIC MICE MODELS FOR GENE FUNCTION, WHEREIN THE TRANSGENIC MICE ARE CHARACTERIZED BY HAVING ALTERED SEROTONIN 5-HT6 RECEPTOR GENE FUNCTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-05-09 US claimed
WO-2000006082-A2 TREATMENT OF ANXIETY DISORDERS ELI LILLY AND COMPANY (US) 2000-02-10 WO claimed
EP-0835107-A1 THE USE OF ALPHA-1C-SELECTIVE ADRENOCEPTOR AGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1998-04-15 EP claimed
EP-0751790-A4 SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS UNIV PENNSYLVANIA (US) 1997-06-11 EP claimed
EP-0751790-A1 SEROTONIN (5-HT 1A) RECEPTOR LIGANDS AND IMAGING AGENTS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1997-01-08 EP claimed
WO-1996038143-A1 THE USE OF ALPHA-1C-SELECTIVE ADRENOCEPTOR AGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1996-12-05 WO claimed