Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.97 |
| ▸ | HTR2A | P28223 | 7/20 | 0.97 |
| ▸ | HTR1A | P08908 | 7/20 | 0.97 |
| ▸ | HTR1D | P28221 | 6/20 | 0.97 |
| ▸ | HTR1B | P28222 | 4/20 | 0.97 |
| ▸ | HTR7 | P34969 | 3/20 | 0.97 |
| ▸ | HTR2B | P41595 | 2/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.97 |
| ▸ | TSHR | P16473 | 2/20 | 0.97 |
| ▸ | HTR5A | P47898 | 2/20 | 0.97 |
| ▸ | HTR6 | P50406 | 2/20 | 0.97 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.97 |
| ▸ | HTR3B | O95264 | 1/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.97 |
| ▸ | DRD1 | P21728 | 1/20 | 0.97 |
| ▸ | HTR1E | P28566 | 1/20 | 0.97 |
| ▸ | HTR1F | P30939 | 1/20 | 0.97 |
| ▸ | DRD3 | P35462 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serotonin SCHEMBL30057954 | 0.98 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL29349412 | 0.98 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL1495 | 0.98 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL183226 | 0.98 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL25341783 | 0.97 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL8208967 | 0.97 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL29669289 | 0.97 | HTR2C (0.97) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL29781387 | 0.97 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL396997 | 0.97 | HTR2C (0.97) | HTR2CHTR2AHTR1AHTR1DHTR1B | |
| Serotonin SCHEMBL1675866 | 0.97 | HTR2C (0.97) | HTR2CHTR2AHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456673-A | Enamel products and methods of use | 纽约州立大学研究基金会 | 2017-02-22 | — | — | CN | disclosed |
| US-8084497-B2 | C-(2-phenyl-cyclohexyl)-methylamine compounds for therapy of fibromyalgia | GRUENENTHAL GMBH (DE) | 2011-12-27 | — | — | US | disclosed |
| US-20100249225-A1 | C-(2-Phenyl-Cyclohexyl)-Methylamine Compounds for the Treatment of Anxiety Disorders | GRUENENTHAL GMBH (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20100004341-A1 | C-(2-Phenyl-Cyclohexyl)-Methylamine Compounds for Therapy of Fibromyalgia | GRUENENTHAL GMBH (DE) | 2010-01-07 | — | — | US | disclosed |
| US-20060258741-A1 | C-(2-phenyl-cyclohexyl)-methylamine compounds for the treatment of anxiety disorders | GRUENENTHAL GMBH | 2006-11-16 | — | — | US | disclosed |
| WO-2006063164-A2 | COMPOSITIONS AND METHODS FOR TREATING NEUROENDOCRINE TUMORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060121040-A1 | Compositions and methods for treating neuroendocrine tumors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258741-A1 | C-(2-phenyl-cyclohexyl)-methylamine compounds for the treatment of anxiety disorders | PNMT, HTR2C, HTR2A | HTR2C 2/4885HTR2A 3/4885HTR1A 8/4885 |
| US-20100004341-A1 | C-(2-Phenyl-Cyclohexyl)-Methylamine Compounds for Therapy of Fibromyalgia | PNMT, HNMT, GNMT | HTR2C 11/4885HTR2A 13/4885HTR1A 47/4885 |
| US-20100249225-A1 | C-(2-Phenyl-Cyclohexyl)-Methylamine Compounds for the Treatment of Anxiety Disorders | PNMT, HTR2C, HTR2A | HTR2C 2/4885HTR2A 3/4885HTR1A 8/4885 |
| US-20060121040-A1 | Compositions and methods for treating neuroendocrine tumors | GSK3B, GSK3A, NEK3 | HTR2C 646/4885HTR2A 817/4885HTR1A 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.