Serotonin

Serotonin

SCHEMBL29349412

NCCc1c[nH]c2ccc(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 1.00
HTR2A P28223 7/20 1.00
HTR1A P08908 7/20 1.00
HTR1D P28221 6/20 1.00
HTR1B P28222 4/20 1.00
HTR7 P34969 3/20 1.00
HTR2B P41595 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP1A2 P05177 2/20 1.00
TSHR P16473 2/20 1.00
HTR5A P47898 2/20 1.00
HTR6 P50406 2/20 1.00
HTR3E A5X5Y0 1/20 1.00
HTR3B O95264 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C9 P11712 1/20 1.00
DRD1 P21728 1/20 1.00
HTR1E P28566 1/20 1.00
HTR1F P30939 1/20 1.00
DRD3 P35462 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serotonin SCHEMBL183226 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL30057954 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL1495 1.00 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL8208967 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29781387 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL25341783 0.98 HTR2C (1.00) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL29669289 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL396997 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL3091827 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B
Serotonin SCHEMBL1675866 0.98 HTR2C (0.97) HTR2CHTR2AHTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8683 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747247-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF Apogee Pharmaceuticals, Inc. (CA) 2026-05-27 EP claimed
CN-122036690-A Heteroaromatic ring compound, pharmaceutical composition and application thereof 马应龙药业集团股份有限公司 2026-05-15 CN claimed
CN-122017138-A Comprehensive biomarker response Index (IBR) based photoaging micro-plastic composite toxicity detection and risk judgment method 生态环境部华南环境科学研究所(生态环境部生态环境应急研究所) 2026-05-12 CN claimed
US-12624036-B2 Method of treating post-traumatic stress disorder INTRA-CELLULAR THERAPIES, INC. (US) 2026-05-12 US claimed
US-12624037-B2 Method of treating agitation, aggressive behavior, and impulse control disorder INTRA-CELLULAR THERAPIES, INC. (US) 2026-05-12 US claimed
EP-4724052-A1 COMPOSITIONS AND METHODS FOR TREATING HEMIPLEGIC MIGRAINE Schedule 1 Therapeutics, Inc. (US) 2026-04-15 EP claimed
EP-4299107-B1 SYSTEMS FOR DELIVERING THERAPY USING AN AURICULAR STIMULATION DEVICE SPARK BIOMEDICAL INC (US) 2026-04-08 EP claimed
US-12594388-B2 Device to deliver a predetermined amount of a substance to a natural orifice of the body APTARGROUP, INC. (US) 2026-04-07 US claimed
US-20260085284-A1 METHOD FOR TRANS-DIFFERENTIATING NON-NEURONAL CELLS INTO NEURONS AND USE THEREOF SHANGHAI GENEMAGIC BIOSCIENCES CO., LTD. (CN) 2026-03-26 US claimed
US-20260069616-A1 COMPOSITIONS COMPRISING CANNABINOIDS AND METHODS OF USE SCHEDULE 1 THERAPEUTICS, INC. (US) 2026-03-12 US claimed
US-20220081409-A1 PDE9 INHIBITOR AND USE THEREOF TRANSTHERA SCIENCES (NANJING), INC. (CN) 2022-03-17 US claimed
CN-114159438-A Application of hypnagazine and derivatives thereof in preparation of medicaments for treating depression and prepared antidepressant medicaments 首都医科大学附属北京安定医院 2022-03-11 CN claimed
EP-3958859-A1 PREVENTING AND TREATING MALARIA Shine, Ian Basil (US) 2022-03-02 EP claimed
CN-114081175-A Composition and application thereof in preparation of sleep improvement product 内蒙古伊利实业集团股份有限公司 2022-02-25 CN claimed
EP-3955936-A1 TREATMENT OF DEPRESSION AND OTHER VARIOUS DISORDERS WITH PSILOCYBIN COMPASS Pathfinder Limited (GB) 2022-02-23 EP claimed
EP-3953000-A1 CELL MEMBRANE PERMEABILITY RESTORING THERAPY Shine, Ian Basil (US) 2022-02-16 EP claimed
WO-2022023759-A2 METHODS OF PREPARING SOLID PARTICULATE MATERIALS MICROPORE TECHNOLOGIES LIMITED (GB) 2022-02-03 WO claimed
WO-2022023812-A1 EXTENDED RELEASE 5-HT RECEPTOR AGONISTS FOR NEUROLOGICAL CONDITIONS DIAMOND THERAPEUTICS INC. (CA) 2022-02-03 WO claimed
CN-114007692-A Methods and compositions for treating epilepsy 加利福尼亚大学董事会 2022-02-01 CN claimed
WO-2022017440-A1 5-HT2A RECEPTOR INHIBITOR OR INVERSE AGONIST, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 山东绿叶制药有限公司 2022-01-27 WO claimed