Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 5/20 | 0.50 |
| ▸ | IGF1R | P08069 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049130 | 0.83 | CYP3A4 (0.59) | MEN1KMT2AGSK3AGSK3BALDH1A1 | |
| SCHEMBL13774950 | 0.83 | CYP3A4 (0.54) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL5755656 | 0.81 | NTRK1 (0.58) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL14950255 | 0.80 | MAPK8 (0.56) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11684045 | 0.80 | PGR (0.54) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL10383929 | 0.79 | GAA (0.44) | MEN1GAAKMT2AATMALDH1A1 | |
| SCHEMBL11771158 | 0.79 | SMN1; SMN2 (0.40) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL5198556 | 0.78 | NTRK1 (0.72) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL29251945 | 0.77 | NTRK1 (0.50) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11769686 | 0.77 | ALDH1A1 (0.40) | NTRK1NTRK2NTRK3MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085268-A | Disubstituted s-triazines | ARMSTRONG CORK COMPANY (US) | 1978-04-18 | — | — | US | disclosed |