Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 11/20 | 0.67 |
| ▸ | MME | P08473 | 10/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12975100 | 1.00 | MMEL1 (0.67) | MMEL1MMEACECTSL | |
| SCHEMBL12975086 | 0.94 | MMEL1 (0.59) | MMEL1MMEACECTSL | |
| SCHEMBL2779899 | 0.91 | MMEL1 (0.62) | MMEL1MMEACECTSL | |
| SCHEMBL2779890 | 0.91 | MMEL1 (0.62) | MMEL1MMEACECTSL | |
| SCHEMBL6122512 | 0.86 | MMEL1 (0.53) | MMEL1MMEACECTSL | |
| SCHEMBL8532740 | 0.86 | MMEL1 (0.53) | MMEL1MMEACECTSL | |
| SCHEMBL3703250 | 0.85 | MMEL1 (0.51) | MMEL1MMEACECTSL | |
| SCHEMBL16588774 | 0.85 | MMEL1 (0.51) | MMEL1MMEACECTSL | |
| SCHEMBL1912590 | 0.85 | MMEL1 (0.67) | MMEL1MMEACE | |
| SCHEMBL17993645 | 0.84 | MME (0.51) | MMEL1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594556-A1 | Substituted aminopropionic derivatives as neprilysin inhibitors | Novartis AG (CH) | 2013-05-22 | — | — | EP | disclosed |