Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14954673 | 0.78 | TSHR (0.52) | TSHRALDH1A1HTTMAPK1KMT2A | |
| SCHEMBL1974668 | 0.78 | KIF11 (0.48) | TSHRALDH1A1HTTKIF11MAPK1 | |
| SCHEMBL9888403 | 0.75 | SMN1; SMN2 (0.48) | TSHRALDH1A1HTTMAPK1CYP2D6 | |
| SCHEMBL27953401 | 0.75 | TSHR (0.40) | TSHRALDH1A1HTTIDH1KIF11 | |
| SCHEMBL10865897 | 0.75 | TAAR1 (0.48) | TSHRALDH1A1HTTMAPK1CYP2D6 | |
| SCHEMBL9317928 | 0.75 | MAPK1 (0.41) | TSHRALDH1A1HTTMAPK1KMT2A | |
| SCHEMBL19419845 | 0.75 | CYP1A2 (0.47) | TSHRALDH1A1HTTKMT2ACYP2D6 | |
| SCHEMBL28661137 | 0.75 | ALDH1A1 (0.37) | TSHRALDH1A1HTTMAPK1 | |
| SCHEMBL7741027 | 0.73 | TSHR (0.47) | TSHRALDH1A1HTTIDH1KIF11 | |
| SCHEMBL4395774 | 0.73 | TAAR1 (0.42) | TSHRALDH1A1HTTKIF11MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822248-B2 | Polysiloxane composition, hardened material and optical device | KANEKA CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9688851-B2 | Polysiloxane composition, hardened material and optical device | KANEKA CORPORATION (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20150203677-A1 | POLYSILOXANE COMPOSITION, HARDENED MATERIAL AND OPTICAL DEVICE | KANEKA CORPORATION (JP) | 2015-07-23 | — | — | US | disclosed |
| US-20130131264-A1 | POLYSILOXANE COMPOSITION, HARDENED MATERIAL AND OPTICAL DEVICE | KANEKA CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |