Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271193 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPT | |
| SCHEMBL10795829 | 0.78 | MAPT (0.34) | ALDH1A1TSHRTP53MAPT | |
| SCHEMBL1271103 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL1493187 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHRGAA | |
| SCHEMBL3422339 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHRTP53MAPTKDM4E | |
| SCHEMBL23514189 | 0.77 | TSHR (0.33) | ALDH1A1TSHRTP53MAPTESR1 | |
| SCHEMBL8770161 | 0.76 | MAPT (0.35) | ALDH1A1TSHRTP53MAPTESR1 | |
| SCHEMBL1271110 | 0.76 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL2288347 | 0.74 | MAPT (0.34) | ALDH1A1TSHRTP53MAPTESR1 | |
| SCHEMBL15302238 | 0.74 | ALDH1A1 (0.31) | ALDH1A1TSHRTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620441-B1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | KANEKA CORP (JP) | 2018-10-31 | — | — | EP | disclosed |
| CN-104744944-B | Polysiloxanes based composition, solidfied material and optics | 株式会社钟化 | 2017-12-19 | — | — | CN | disclosed |
| US-9822248-B2 | Polysiloxane composition, hardened material and optical device | KANEKA CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9698320-B2 | Modified product of polyhedral structure polysiloxane, polyhedral structure polysiloxane composition, cured product, and optical semiconductor device | KANEKA CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| US-9688851-B2 | Polysiloxane composition, hardened material and optical device | KANEKA CORPORATION (JP) | 2017-06-27 | — | — | US | disclosed |
| CN-103119048-B | Modified polyhedral polysiloxane, polyhedral polysiloxane composition, cured product, and optical semiconductor device | KANEKA CORP. (JP) | 2016-06-01 | — | — | CN | disclosed |
| CN-102918110-B | Polysiloxane composition, cured product and optical device | KANEKA CORP. (JP) | 2015-08-12 | — | — | CN | disclosed |
| US-20150203677-A1 | POLYSILOXANE COMPOSITION, HARDENED MATERIAL AND OPTICAL DEVICE | KANEKA CORPORATION (JP) | 2015-07-23 | — | — | US | disclosed |
| CN-104744944-A | Polysiloxane Composition, Hardened Material And Optical Device | KANEKA CORP | 2015-07-01 | — | — | CN | disclosed |
| US-20130237663-A1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | KANEKA CORPORATION (JP) | 2013-09-12 | — | — | US | disclosed |
| EP-2620441-A1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | Kaneka Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-20130131264-A1 | POLYSILOXANE COMPOSITION, HARDENED MATERIAL AND OPTICAL DEVICE | KANEKA CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| CN-102918110-A | Polysiloxane composition, cured product and optical device | KANEKA CORP | 2013-02-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237663-A1 | MODIFIED PRODUCT OF POLYHEDRAL STRUCTURE POLYSILOXANE, POLYHEDRAL STRUCTURE POLYSILOXANE COMPOSITION, CURED PRODUCT, AND OPTICAL SEMICONDUCTOR DEVICE | HSF1, PIEZO1, HSP90AA1 | ALDH1A1 2757/4885TSHR 4560/4885TP53 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.