Indole

Indole

SCHEMBL149556

CC(=O)C(C(=O)O)[C@H](N)C(=O)O.c1ccc2[nH]ccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
ITGB2 P05107 1/20 0.49
ICAM1 P05362 1/20 0.49
ITGAL P20701 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
AHR P35869 1/20 0.49
ADK P55263 1/20 0.49
PTGS2 P35354 1/20 0.38
CTNNB1 P35222 2/20 0.37
WNT3A P56704 2/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
ENPP2 Q13822 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 2/20 0.36
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL3738189 1.00 TRPA1 (0.49) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL2262674 0.87 TRPA1 (0.53) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL22750244 0.87 TRPA1 (0.53) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL9418736 0.85 TRPA1 (0.59) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL27647341 0.85 TRPA1 (0.59) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL2948635 0.85 TRPA1 (0.59) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL22582342 0.83 TRPA1 (0.46) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL4212518 0.83 TRPA1 (0.46) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL5805750 0.81 TRPA1 (0.44) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL22322146 0.80 TRPA1 (0.42) TRPA1CA1CA2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4228397-A1 METHODS AND COMPOSITIONS FOR AXILLARY SHOOT MICROPROPAGATION OF CANNABIS AND RELATED PLANTS Phytotech Labs, Inc. (US) 2023-08-23 EP claimed
WO-2022081767-A1 METHODS AND COMPOSITIONS FOR AXILLARY SHOOT MICROPROPAGATION OF CANNABIS AND RELATED PLANTS PHYTOTECH LABS, INC. (US) 2022-04-21 WO claimed
US-20220110278-A1 METHODS AND COMPOSITIONS FOR AXILLARY SHOOT MICROPROPAGATION OF CANNABIS AND RELATED PLANTS JUSHI IP, LLC 2022-04-14 US claimed
US-9465040-B2 Method for profiling phytohormone levels in plant tissue BASF PLANT SCIENCE COMPANY GMBH (DE) 2016-10-11 US claimed
US-20140147925-A1 Method for Profiling Phytohormone Levels in Plant Tissue BASF PLANT SCIENCE COMPANY GMBH (DE) 2014-05-29 US claimed
EP-2697640-A1 METHOD FOR PROFILING PHYTOHORMONE LEVELS IN PLANT TISSUE BASF Plant Science Company GmbH (DE) 2014-02-19 EP claimed
WO-2012140603-A1 METHOD FOR PROFILING PHYTOHORMONE LEVELS IN PLANT TISSUE BASF PLANT SCIENCE COMPANY GMBH (DE) 2012-10-18 WO claimed
US-20120108431-A1 PLANT GROWTH REGULATOR ADDITIVE TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2012-05-03 US claimed
EP-2416653-A2 PLANT GROWTH REGULATOR ADDITIVE Taminco, Naamloze Vennootschap (BE) 2012-02-15 EP claimed
WO-2010116259-A2 PLANT GROWTH REGULATOR ADDITIVE TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2010-10-14 WO claimed
WO-2009018368-A1 COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2009-02-05 WO claimed
US-20250263347-A1 Efficient Process for Manufacturing Bionutritional Compositions for Plants and Soils ENVIROKURE, INCORPORATED (US) 2025-08-21 US disclosed
US-20250072433-A1 ORGANIC CONCENTRATED VITAMINE-PHYTOHORMONE WITH NATURAL BIO-STIMULANT PROPERTIES AS FERTILIZER CONCENTRATED EXTRACT OF DUCKWEED ARACEA FAMILY OF PLANTS FORMALY KNOWN AS LEMNACEAE SINGLE OR COMBINED SPECIES THAT CAN INCLUDE ALSO COMPOUNDED MULTIPLE FORMULATED AQUATIC PLANTS EXTRACTS TO NATURALY INCREASE PLANT GROWTH AND CROP YIELDS GREENBERG CORDERO EDWARD (US) 2025-03-06 US disclosed
US-11751573-B2 Seaweed composition PORT LOUIS BERNARD (SC) 2023-09-12 US disclosed
US-11529342-B2 Sorbic and benzoic acid and derivatives thereof enhance the activity of a neuropharmaceutical LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2022-12-20 US disclosed
US-20020026659-A1 Developed seed and methods for making the same BALL SEED 2002-02-28 US disclosed
WO-2001003493-A9 DEVELOPED SEED AND METHODS FOR MAKING THE SAME BALL HORTICULTURAL CO (US) 2001-10-18 WO disclosed
WO-2001003493-A1 DEVELOPED SEED AND METHODS FOR MAKING THE SAME BALL HORTICULTURAL COMPANY (US) 2001-01-18 WO disclosed
WO-2000009722-A2 METHODS FOR CONTROLLING GIBBERELLIN LEVELS MONSANTO COMPANY (US) 2000-02-24 WO disclosed
US-5646023-A GENETIC ENGINEERING, SUPPRESSING SUGAR BIOSYNTHESIS IN POTATOES, INHIBITING UDP-GLUCOSE PYROPHOSPHORYLASE J.R. SIMPLOT COMPANY (US) 1997-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108431-A1 PLANT GROWTH REGULATOR ADDITIVE MYB, ING2, AGXT TRPA1 4791/4885CA1 3741/4885CA2 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.