Indole

Indole

SCHEMBL3738189

CC(=O)C(C(=O)O)C(N)C(=O)O.c1ccc2[nH]ccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
ITGB2 P05107 1/20 0.49
ICAM1 P05362 1/20 0.49
ITGAL P20701 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
AHR P35869 1/20 0.49
ADK P55263 1/20 0.49
PTGS2 P35354 1/20 0.38
CTNNB1 P35222 2/20 0.37
WNT3A P56704 2/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
ENPP2 Q13822 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 2/20 0.36
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL149556 1.00 TRPA1 (0.49) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL2262674 0.87 TRPA1 (0.53) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL22750244 0.87 TRPA1 (0.53) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL9418736 0.85 TRPA1 (0.59) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL27647341 0.85 TRPA1 (0.59) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL2948635 0.85 TRPA1 (0.59) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL22582342 0.83 TRPA1 (0.46) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL4212518 0.83 TRPA1 (0.46) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL5805750 0.81 TRPA1 (0.44) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL22322146 0.80 TRPA1 (0.42) TRPA1CA1CA2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066409-A Efficient manufacturing process for biological nutrient compositions for plants and soils 恩维罗库尔股份有限公司 2022-09-16 CN claimed
CN-102438453-A Plant growth regulator additive TAMINCO NV 2012-05-02 CN claimed
CN-122028792-A Use of cyclic ether derivatives as solvents 法国特种经营公司 2026-05-12 CN disclosed
US-20250340495-A1 SLUDGE-DERIVED PLANT BIOSTIMULANT, AND DIRECTIONAL PREPARATION METHOD AND APPLICATION THEREOF UNIV TONGJI (CN) 2025-11-06 US disclosed
WO-2025109091-A1 NEW BIO-BASED ESTERAMIDE MIXTURE AND ITS USE AS SOLVENT SPECIALTY OPERATIONS FRANCE (FR) 2025-05-30 WO disclosed
CN-119730725-A Biodegradable polyesters for use as dispersants and agricultural compositions containing the same 法国特种经营公司 2025-03-28 CN disclosed
US-20250017216-A1 LIQUID CARRIER CONCENTRATE COMPRISING AT LEAST ONE BENEFICIAL MICROORGANISM AND USES THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2025-01-16 US disclosed
US-20250017215-A1 LIQUID CARRIER CONCENTRATE COMPRISING AT LEAST ONE BENEFICIAL MICROORGANISM AND USES THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2025-01-16 US disclosed
US-20250017217-A1 LIQUID CARRIER CONCENTRATE COMPRISING AT LEAST ONE BENEFICIAL MICROORGANISM AND USES THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2025-01-16 US disclosed
US-20250017203-A1 LIQUID CARRIER CONCENTRATE COMPRISING AT LEAST ONE BENEFICIAL MICROORGANISM AND USES THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2025-01-16 US disclosed
US-20240268377-A1 AGROCHEMICAL COMPOSITION CONTAINING A PARTICULAR COPOLYMER DISPERSANT WITH AT LEAST ONE B-CARBOXYETHYL ACRYLATE MONOMER SPECIALTY OPERATIONS FRANCE (FR) 2024-08-15 US disclosed
WO-2013123164-A1 METHOD TO INCREASE PLANT YIELD WILSON JOHN HUGH MCCLEERY (US) 2013-08-22 WO disclosed
CN-102438447-A Safening agent TAMINCO NV 2012-05-02 CN disclosed
CN-102438453-A Plant growth regulator additive TAMINCO NV 2012-05-02 CN disclosed
US-7824914-B2 Flavonoids-rich tissues from Neomarica gracilis and methods for culturing the same TATUNG COMPANY (TW) 2010-11-02 US disclosed
CN-101454455-A DNA binding site of a transcriptional activator useful in gene expression DSM IP ASSETS BV (NL) 2009-06-10 CN disclosed
US-20090028796-A1 PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) 2009-01-29 US disclosed
US-20080311634-A1 Flavonoids-rich tissue from Belamcanda chinensis and methods for culturing the same TATUNG UNIVERSITY (TW) 2008-12-18 US disclosed
US-20080160615-A1 Flavonoids-rich tissues from Neomarica gracilis and methods for culturing the same TATUNG COMPANY AND TATUNG UNIVERSITY 2008-07-03 US disclosed
CN-1568370-A treatment of central nervous system disorders with D-amino acid oxidase and D-aspartate oxidase antagonists GENSET SA (FR) 2005-01-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090028796-A1 PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES IDO1, IDO2, INMT TRPA1 822/4885CA1 2194/4885CA2 1658/4885
US-20250017215-A1 LIQUID CARRIER CONCENTRATE COMPRISING AT LEAST ONE BENEFICIAL MICROORGANISM AND USES THEREOF LRBA, INPP5A, IPO5 TRPA1 411/4885CA1 2997/4885CA2 1772/4885
US-20250017203-A1 LIQUID CARRIER CONCENTRATE COMPRISING AT LEAST ONE BENEFICIAL MICROORGANISM AND USES THEREOF LRBA, DBF4, BROX TRPA1 355/4885CA1 2472/4885CA2 2159/4885
US-20240268377-A1 AGROCHEMICAL COMPOSITION CONTAINING A PARTICULAR COPOLYMER DISPERSANT WITH AT LEAST ONE B-CARBOXYETHYL ACRYLATE MONOMER BROX, AGPS, ATL3 TRPA1 4729/4885CA1 2115/4885CA2 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.