Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907002 | 0.87 | HDAC3 (0.52) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL16761839 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL18183854 | 0.75 | ALDH1A1 (0.62) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL8175968 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL10640944 | 0.73 | KDM4E (0.53) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL24851923 | 0.73 | EGLN1 (0.54) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL16839562 | 0.73 | EGLN1 (0.46) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL8182105 | 0.72 | HDAC3 (0.56) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL8331064 | 0.71 | HDAC3 (0.58) | ALDH1A1TDP1POLBHDAC3HDAC4 | |
| SCHEMBL2565094 | 0.71 | HDAC3 (0.69) | ALDH1A1TDP1POLBHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023858-B2 | Substituted pyrido[2,3-d]pyrimidines as delta-5-desaturase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-05 | — | — | US | disclosed |
| EP-2597095-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20130131050-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131050-A1 | FUSED HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LTB4R2, LTB4R, LTC4S | ALDH1A1 633/4885TDP1 3242/4885POLB 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.