Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838521 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19PTPN1SMN1; SMN2 | |
| SCHEMBL7072808 | 0.86 | HPGD (0.47) | CYP1A2SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL14957621 | 0.83 | HTT (0.43) | CYP1A2SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL8223057 | 0.82 | L3MBTL1 (0.44) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL3459654 | 0.81 | KDM4E (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL1840614 | 0.81 | LMNA (0.47) | CYP1A2CYP2C9CYP2C19PTPN1SMN1; SMN2 | |
| SCHEMBL1836358 | 0.80 | LMNA (0.50) | PTPN1TSHRCNR1CNR2ALDH1A1 | |
| SCHEMBL1837839 | 0.80 | LMNA (0.50) | PTPN1TSHRCNR1CNR2ALDH1A1 | |
| SCHEMBL1837560 | 0.80 | LMNA (0.50) | PTPN1TSHRCNR1CNR2ALDH1A1 | |
| SCHEMBL1837216 | 0.80 | LMNA (0.50) | PTPN1TSHRCNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | CDV3, ETV1, BOLA2; BOLA2B | CYP1A2 2346/4885CYP2C9 3808/4885CYP2C19 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.