Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LIG1 | P18858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26011513 | 0.88 | MAPT (0.42) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL1628363 | 0.86 | TSHR (0.50) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL14957993 | 0.86 | CYP1A2 (0.41) | HPGDTSHRMAPK1HSD17B10MAPT | |
| SCHEMBL978930 | 0.85 | HPGD (0.50) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| 1-Hydroxy-2-Allyloxybenzene SCHEMBL1562951 | 0.84 | GAA (0.59) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL14957621 | 0.83 | HTT (0.43) | HPGDTSHRMAPK1HSD17B10MAPT | |
| SCHEMBL28071261 | 0.81 | TSHR (0.46) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL15814879 | 0.80 | CYP3A4 (0.49) | HPGDTSHRMAPK1HSD17B10LIG1 | |
| SCHEMBL28199074 | 0.80 | CXCR5 (0.45) | HPGDTSHRMAPK1HSD17B10CYP3A4 | |
| SCHEMBL4865834 | 0.80 | HPGD (0.46) | HPGDTSHRMAPK1HSD17B10LIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514290-A | EXTREME PRESSURE LUBRICANTS | MOBIL OIL CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| CN-103180355-B | Phenolic oligomers and preparation method thereof | MEIWA PLASTIC INDUSTRIES, LTD. (JP) | 2015-08-05 | — | — | CN | disclosed |
| US-20130307167-A1 | PHENOLIC OLIGOMER AND METHOD FOR PRODUCING THE SAME | MEIWA PLASTIC INDUSTRIES, LTD. (JP) | 2013-11-21 | — | — | US | disclosed |
| CN-103180355-A | Phenol-type oligomer and process for production thereof | MEIWA PLASTIC IND LTD | 2013-06-26 | — | — | CN | disclosed |
| US-6518048-B2 | Hydrogenation a isophthalic acid derivative | HOFFMANN-LA ROCHE INC. | 2003-02-11 | — | — | US | disclosed |
| US-20010036653-A1 | Stereo-specific synthesis of shimikic acid derivatives with improved efficiency | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-01 | — | — | US | disclosed |
| EP-1146036-A2 | Tamiflu, Gallocarboxylic acid approach | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010036653-A1 | Stereo-specific synthesis of shimikic acid derivatives with improved efficiency | DDC, ACE, NEU1 | HPGD 443/4885TSHR 3324/4885MAPK1 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.