Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14958424 | 1.00 | MAPT (0.39) | MAPTL3MBTL1TDP1NSD2POLB | |
| SCHEMBL14958425 | 1.00 | MAPT (0.39) | MAPTL3MBTL1TDP1NSD2POLB | |
| SCHEMBL14958413 | 0.84 | ALDH1A1 (0.46) | MAPTTDP1HSD17B10KMT2AMEN1 | |
| SCHEMBL21354382 | 0.78 | NR4A2 (0.40) | MAPTL3MBTL1TDP1POLBKMT2A | |
| SCHEMBL21354384 | 0.78 | NR4A2 (0.40) | MAPTL3MBTL1TDP1POLBKMT2A | |
| SCHEMBL20068336 | 0.76 | MYC (0.49) | MAPTTDP1HSD17B10KMT2AMEN1 | |
| SCHEMBL14957953 | 0.72 | NR4A2 (0.41) | MAPTTDP1RECQLHSD17B10KMT2A | |
| SCHEMBL7824329 | 0.69 | L3MBTL1 (0.72) | MAPTL3MBTL1TDP1NSD2POLB | |
| SCHEMBL7826399 | 0.69 | L3MBTL1 (0.72) | MAPTL3MBTL1TDP1NSD2POLB | |
| SCHEMBL7824322 | 0.69 | L3MBTL1 (0.72) | MAPTL3MBTL1TDP1NSD2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782449-B1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ANACOR PHARMACEUTICALS INC (US) | 2016-08-03 | — | — | EP | disclosed |
| EP-2782449-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| US-8546357-B2 | Boron-containing small molecules for controlling ectoparasites | ELI LILLY AND COMPANY (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2013078071-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, RB1 | MAPT 461/4885L3MBTL1 2465/4885TDP1 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.