Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14958424 | 0.84 | MAPT (0.39) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14958426 | 0.84 | MAPT (0.39) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14958425 | 0.84 | MAPT (0.39) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21354384 | 0.82 | NR4A2 (0.40) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21354382 | 0.82 | NR4A2 (0.40) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20068336 | 0.80 | MYC (0.49) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL14957953 | 0.76 | NR4A2 (0.41) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20294474 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27985191 | 0.72 | LMNA (0.50) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL5786109 | 0.70 | CYP1A2 (0.54) | ALDH1A1GAASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3525590-B1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-08-20 | — | — | EP | disclosed |
| CN-110381738-B | Pesticidal and parasiticidal vinyl isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2021-07-16 | — | — | CN | disclosed |
| US-10653144-B2 | Pesticidal and parasiticidal vinyl isoxazoline compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-05-19 | — | — | US | disclosed |
| US-10653144-B2 | Pesticidal and parasiticidal vinyl isoxazoline compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190281829-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-09-19 | — | — | US | disclosed |
| US-20190281829-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-09-19 | — | — | US | disclosed |
| EP-3525590-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-08-21 | — | — | EP | disclosed |
| WO-2018071535-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | MERIAL, INC. (US) | 2018-04-19 | — | — | WO | disclosed |
| WO-2018071535-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | MERIAL, INC. (US) | 2018-04-19 | — | — | WO | disclosed |
| EP-2782449-B1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ANACOR PHARMACEUTICALS INC (US) | 2016-08-03 | — | — | EP | disclosed |
| EP-2782449-B1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ANACOR PHARMACEUTICALS INC (US) | 2016-08-03 | — | — | EP | disclosed |
| EP-2782449-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| US-8546357-B2 | Boron-containing small molecules for controlling ectoparasites | ELI LILLY AND COMPANY (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2013078071-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078071-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10653144-B2 | Pesticidal and parasiticidal vinyl isoxazoline compounds | CYP4X1, PRDX1, PRDX2 | ALDH1A1 800/4885GAA 2704/4885SMN1; SMN2 3047/4885 |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, RB1 | ALDH1A1 4298/4885GAA 317/4885SMN1; SMN2 1546/4885 |
| US-20190281829-A1 | PESTICIDAL AND PARASITICIDAL VINYL ISOXAZOLINE COMPOUNDS | CYP4X1, PRDX1, PRDX2 | ALDH1A1 800/4885GAA 2704/4885SMN1; SMN2 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.