Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.38 |
| ▸ | DRD3 | P35462 | 13/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793781 | 0.84 | DRD3 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL2693371 | 0.84 | DRD3 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL1793783 | 0.84 | DRD3 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL11807764 | 0.80 | ADH1C (0.47) | DRD2DRD3 | |
| SCHEMBL6680792 | 0.80 | GNAI3 (0.37) | DRD2DRD3DRD4 | |
| SCHEMBL3374356 | 0.73 | DRD3 (0.44) | DRD2DRD3DRD4 | |
| SCHEMBL3376550 | 0.73 | DRD3 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL24220857 | 0.71 | — | — | |
| SCHEMBL3490832 | 0.71 | — | — | |
| SCHEMBL8852104 | 0.71 | SLC6A2 (0.43) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |