Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865807 | 0.91 | DRD3 (0.48) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL14432505 | 0.89 | DRD3 (0.44) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL3374356 | 0.89 | DRD3 (0.44) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL3370178 | 0.88 | — | — | |
| SCHEMBL516016 | 0.88 | ADH1A (0.52) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL1793781 | 0.87 | DRD3 (0.43) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL20307362 | 0.87 | DRD3 (0.43) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL1793783 | 0.87 | DRD3 (0.43) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL2693371 | 0.87 | DRD3 (0.43) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL736484 | 0.87 | DRD3 (0.47) | DRD3DRD2DRD4HTR1AFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365605-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-11-16 | — | — | US | disclosed |
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |
| CN-110467532-B | Synthetic method of aryl cyclopropylamine compound | 华东理工大学 | 2020-09-29 | — | — | CN | disclosed |
| CN-110467532-A | A kind of synthetic method of aryl cyclopropylamine class compound | UNIV EAST CHINA SCIENCE & TECH | 2019-11-19 | — | — | CN | disclosed |
| EP-2300013-B1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMA INC (US) | 2017-09-06 | — | — | EP | disclosed |
| EP-3210609-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2298926-A1 | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof | The Trustees of The University of Pennsylvania (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| EP-1594878-B1 | AVERMECTIN MONOSACCHARIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | MERIAL LTD (GB) | 2008-06-04 | — | — | EP | disclosed |
| EP-1366036-A2 | COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF CYTOCHROME P450RAI | Allergan, Inc. (US) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002018361-A2 | COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF CYTOCHROME P450RAI | ALLERGAN, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | DRD3 2098/4885DRD2 3478/4885DRD4 3704/4885 |
| US-20230365605-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | SOST, SOS1, SOS2 | DRD3 3998/4885DRD2 4452/4885DRD4 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.