Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 3/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | GIPR | P48546 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20879839 | 0.94 | GCGR (0.39) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL14960510 | 0.94 | GCGR (0.39) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL18790138 | 0.94 | GCGR (0.39) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL14959092 | 0.90 | RXFP1 (0.42) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL14959097 | 0.87 | MAPK14 (0.38) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL14959087 | 0.87 | ACKR3 (0.40) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL13327392 | 0.85 | RXFP1 (0.42) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL14960509 | 0.85 | RXFP1 (0.42) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL18790161 | 0.85 | RXFP1 (0.42) | UBE2MDCUN1D1GCGRGIPRRXFP1 | |
| SCHEMBL15088237 | 0.85 | RXFP1 (0.37) | UBE2MDCUN1D1GCGRGIPRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445515-B2 | C5aR antagonists | CHEMOCENTRYX, INC. (US) | 2013-05-21 | — | — | US | disclosed |