SCHEMBL14959709

SCHEMBL14959709

CCCSCc1ncccc1SC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 1/20 0.33
SLC47A1 Q96FL8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5489047 0.87 L3MBTL1 (0.40) SLC47A1
SCHEMBL14959710 0.84 PDE5A (0.36) PDE5ASLC47A1
SCHEMBL3087081 0.79 ALDH1A1 (0.38) SLC47A1
SCHEMBL3360367 0.78 KDM4E (0.33)
SCHEMBL3081181 0.77 SLC22A12 (0.32)
SCHEMBL3091847 0.76 IDO1 (0.41)
SCHEMBL3068375 0.76 AOC3 (0.33)
SCHEMBL3079212 0.76 ALDH1A1 (0.48)
SCHEMBL3081194 0.76 AOC3 (0.43)
SCHEMBL3068314 0.74 GBA1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445476-B2 Carbacephem β-lactam antibiotics ACHAOGEN, INC. (US) 2013-05-21 US disclosed