Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081181 | 0.87 | SLC22A12 (0.32) | KDM4EALDH1A1HSD17B10HPGDCHRM2 | |
| SCHEMBL3068314 | 0.86 | GBA1 (0.37) | KDM4EALDH1A1HSD17B10HPGDCHRM2 | |
| SCHEMBL3087081 | 0.80 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDPOLBLMNA | |
| SCHEMBL3068316 | 0.78 | SLC22A12 (0.33) | KDM4EALDH1A1HSD17B10HPGDCHRM2 | |
| SCHEMBL14959709 | 0.78 | PDE5A (0.33) | — | |
| SCHEMBL13095199 | 0.77 | PDK2 (0.37) | KDM4EALDH1A1HSD17B10HPGDCHRM2 | |
| SCHEMBL5489047 | 0.77 | L3MBTL1 (0.40) | CYP2C19 | |
| SCHEMBL3091847 | 0.74 | IDO1 (0.41) | KDM4EHPGDPOLBLMNA | |
| SCHEMBL3079212 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10HPGDCHRM2 | |
| SCHEMBL3089376 | 0.70 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030811-A2 | CARBACEPHEM β-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |