SCHEMBL1496063

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27789698	0.86	MEN1 (0.41)	MEN1KMT2AALDH1A1POLBHPGD
	SCHEMBL1496043	0.85	ALDH1A1 (0.48)	MAPTMEN1KMT2AMAPK1ALDH1A1
	SCHEMBL30933991	0.85	ALDH1A1 (0.48)	MAPTMEN1KMT2AMAPK1ALDH1A1
	SCHEMBL5554094	0.80	CDC25B (0.45)	MAPTMEN1KMT2AMAPK1ALDH1A1
	SCHEMBL1495953	0.79	KMT2A (0.46)	MAPTKMT2AMAPK1ALDH1A1POLB
	SCHEMBL1495954	0.79	KMT2A (0.46)	MAPTKMT2AMAPK1ALDH1A1POLB
	SCHEMBL8370179	0.78	MAPT (0.61)	MAPTMEN1KMT2AMAPK1ALDH1A1
	SCHEMBL1495921	0.78	CDC25B (0.54)	KMT2AALDH1A1CDC25BCDC25ACDC25C
	SCHEMBL30933993	0.78	CDC25B (0.54)	KMT2AALDH1A1CDC25BCDC25ACDC25C
	SCHEMBL1495893	0.78	THRB (0.45)	MAPTMEN1KMT2AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.