Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496043 | 0.94 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL30933991 | 0.94 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL30933993 | 0.90 | CDC25B (0.54) | CDC25BALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL1495921 | 0.90 | CDC25B (0.54) | CDC25BALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL1495953 | 0.82 | KMT2A (0.46) | MAPTALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL1495954 | 0.82 | KMT2A (0.46) | MAPTALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL1495893 | 0.80 | THRB (0.45) | MAPTALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL1496063 | 0.80 | MAPT (0.47) | CDC25BMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL4837515 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA | |
| SCHEMBL8370179 | 0.79 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-A2 | VASOPRESSIN V1A ANTAGONISTS | Ferring B.V. (NL) | 2007-05-09 | — | — | EP | disclosed |
| EP-1660501-A2 | PIPERAZINES AS OXYTOCIN AGONISTS | FERRING B.V. (NL) | 2006-05-31 | — | — | EP | disclosed |
| WO-2006021213-A2 | VASOPRESSIN V1A ANTAGONISTS | FERRING B.V. (NL) | 2006-03-02 | — | — | WO | disclosed |
| WO-2005023812-A2 | PIPERAZINES AS OXYTOCIN AGONISTS | FERRING B.V. (NL) | 2005-03-17 | — | — | WO | disclosed |