Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196533 | 0.94 | MEN1 (0.44) | SIRT6SIRT1GLP1RSIRT5TLR2 | |
| SCHEMBL22225476 | 0.84 | SIRT6 (0.52) | SIRT6SIRT1GLP1RSIRT5TLR2 | |
| SCHEMBL27270149 | 0.83 | MEN1 (0.44) | SIRT6SIRT1GLP1RTLR2MEN1 | |
| SCHEMBL15256905 | 0.83 | SIRT6 (0.58) | SIRT6SIRT1GLP1RSIRT5TLR2 | |
| SCHEMBL12196488 | 0.82 | TLR2 (0.43) | SIRT6SIRT1GLP1RTLR2MEN1 | |
| SCHEMBL12196529 | 0.82 | MEN1 (0.43) | SIRT6SIRT1GLP1RTLR2MEN1 | |
| SCHEMBL13749785 | 0.82 | SIRT6 (0.48) | SIRT6SIRT1GLP1RSIRT5TLR2 | |
| SCHEMBL13635152 | 0.81 | SIRT6 (0.59) | SIRT6SIRT1GLP1RSIRT5TLR2 | |
| SCHEMBL22020896 | 0.81 | SIRT6 (0.54) | SIRT6SIRT1SIRT5TLR2FOLH1 | |
| SCHEMBL23451121 | 0.79 | PLA2G2A (0.47) | SIRT6SIRT1GLP1RSIRT5TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130130979-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130130979-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | SIRT6 3735/4885SIRT1 3966/4885GLP1R 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.