Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424313 | 0.92 | SIRT5 (0.48) | SIRT6SIRT1SIRT5ALBPTPN2 | |
| SCHEMBL18291772 | 0.84 | SIRT6 (0.45) | SIRT6SIRT1SIRT5CA1CA2 | |
| SCHEMBL12311706 | 0.83 | SIRT6 (0.57) | SIRT6SIRT1SIRT5ALBPTPN2 | |
| SCHEMBL12519427 | 0.82 | GNAI3 (0.52) | SIRT6SIRT1SIRT5TLR2ROCK2 | |
| SCHEMBL12311708 | 0.82 | SIRT5 (0.65) | SIRT6SIRT1SIRT5ALBPTPN2 | |
| SCHEMBL13635157 | 0.82 | SIRT5 (0.65) | SIRT6SIRT1SIRT5ALBPTPN2 | |
| SCHEMBL24817235 | 0.81 | TLR2 (0.52) | SIRT6SIRT1SIRT5TLR2GRIA1 | |
| SCHEMBL14960655 | 0.81 | SIRT6 (0.49) | SIRT6SIRT1SIRT5CA1CA2 | |
| SCHEMBL14004794 | 0.81 | SIRT6 (0.42) | SIRT6SIRT1TLR2FOLH1MEN1 | |
| SCHEMBL14004680 | 0.80 | SIRT6 (0.41) | SIRT6SIRT1CA1CA2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102660-A1 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES, SUCH AS HISTAMINE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-05-22 | — | — | WO | disclosed |