Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KCNH3 | Q9ULD8 | 5/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073745 | 0.83 | POLB (0.64) | POLBKCNH3IDH2NFKB1ALDH1A1 | |
| SCHEMBL14207307 | 0.75 | KCNH3 (0.69) | POLBKCNH3GBA1NFKB1NPC1 | |
| SCHEMBL2453133 | 0.74 | RAB9A (0.61) | POLBKCNH3IDH2NFKB1ALDH1A1 | |
| SCHEMBL10359056 | 0.73 | GBA1 (0.75) | POLBKCNH3GBA1NFKB1ALDH1A1 | |
| SCHEMBL30240628 | 0.72 | NFKB1 (0.76) | POLBKCNH3NFKB1NPC1RAB9A | |
| SCHEMBL762506 | 0.72 | NFKB1 (0.76) | POLBKCNH3NFKB1NPC1RAB9A | |
| SCHEMBL15984404 | 0.70 | KCNH3 (0.51) | KCNH3IDH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12422594 | 0.70 | RHOA (0.55) | KCNH3NPC1RAB9AMAPTHTT | |
| SCHEMBL12716472 | 0.70 | NPC1 (0.39) | POLBKCNH3GBA1NPC1RAB9A | |
| SCHEMBL14583076 | 0.68 | KCNH3 (0.50) | POLBKCNH3IDH2NFKB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130129989-A1 | AZAPHTHALOCYANINES AND THEIR USE IN INK JET PRINTING | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2013-05-23 | — | — | US | disclosed |