Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964315 | 0.85 | IDO1 (0.32) | IDO1TDO2 | |
| SCHEMBL14462458 | 0.83 | CYP1A2 (0.38) | IDO1TDO2L3MBTL1SMN1; SMN2 | |
| SCHEMBL15093370 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL14964179 | 0.81 | HPGD (0.36) | IDO1 | |
| SCHEMBL14964172 | 0.80 | IDO1 (0.33) | IDO1 | |
| SCHEMBL16581924 | 0.80 | MAPK1 (0.33) | IDO1TDO2SMN1; SMN2 | |
| SCHEMBL14964328 | 0.80 | IDO1 (0.37) | IDO1TDO2SMN1; SMN2 | |
| SCHEMBL15093281 | 0.79 | IDO1 (0.33) | IDO1TDO2SMN1; SMN2 | |
| SCHEMBL5631435 | 0.79 | IDO1 (0.38) | IDO1TDO2L3MBTL1SMN1; SMN2 | |
| SCHEMBL5631440 | 0.79 | IDO1 (0.38) | IDO1TDO2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |