Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893838 | 0.94 | MCHR1 (0.72) | MCHR1MEN1KMT2AKDRPGR | |
| SCHEMBL6897973 | 0.88 | MCHR1 (0.75) | MCHR1MEN1KMT2ANPC1TP53 | |
| SCHEMBL6892162 | 0.87 | MCHR1 (0.71) | MCHR1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL6923947 | 0.84 | MCHR1 (0.66) | MCHR1KDRTSHRCYP1A2POLB | |
| SCHEMBL12531267 | 0.84 | MCHR1 (0.54) | MCHR1MEN1KMT2AKDRKDM4E | |
| SCHEMBL10039646 | 0.83 | MCHR1 (0.68) | MCHR1MEN1KMT2ANPC1TP53 | |
| SCHEMBL6924829 | 0.83 | MCHR1 (0.64) | MCHR1KDRCYP1A2POLBCYP3A4 | |
| SCHEMBL12531392 | 0.83 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL12531391 | 0.83 | MCHR1 (0.67) | MCHR1MEN1KMT2ANPC1TP53 | |
| SCHEMBL10039400 | 0.83 | MCHR1 (0.67) | MCHR1MEN1KMT2ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130129626-A1 | IN VIVO IMAGING AGENTS | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-23 | — | — | US | disclosed |
| US-20130129625-A1 | IN VIVO IMAGING AGENTS | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129625-A1 | IN VIVO IMAGING AGENTS | CCR5, CCR2, CX3CR1 | MCHR1 74/4885MEN1 1111/4885KMT2A 4799/4885 |
| US-20130129626-A1 | IN VIVO IMAGING AGENTS | CCR5, CCR2, CX3CR1 | MCHR1 74/4885MEN1 1111/4885KMT2A 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.