Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.49 |
| ▸ | POLB | P06746 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15618363 | 0.78 | DNMT1 (0.62) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL1496461 | 0.77 | MEN1 (0.47) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL15618423 | 0.71 | MAPK10 (0.53) | MEN1KMT2APOLBRAB9ACASP6 | |
| SCHEMBL6816361 | 0.70 | POLB (0.73) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL23867550 | 0.68 | POLB (0.76) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL1568578 | 0.68 | CYP3A4 (0.70) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL10817708 | 0.67 | POLB (0.68) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL7665966 | 0.66 | HTR1F (0.61) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL1496783 | 0.66 | MEN1 (0.54) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL10813685 | 0.66 | POLB (0.75) | MEN1KMT2APOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |