Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496783 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9APOLBSMN1; SMN2 | |
| SCHEMBL3930758 | 0.79 | PTGER4 (0.51) | MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL3970983 | 0.78 | PTGER4 (0.50) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL15618365 | 0.77 | DNMT1 (0.63) | MEN1KMT2ARAB9APOLBSMN1; SMN2 | |
| SCHEMBL1496460 | 0.77 | MEN1 (0.49) | MEN1KMT2ARAB9APOLBSMN1; SMN2 | |
| SCHEMBL13876936 | 0.76 | PTGER4 (0.51) | ALDH1A1ALOX15TP53 | |
| SCHEMBL4968818 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3975552 | 0.75 | PTGER4 (0.47) | RAB9ASMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL5881733 | 0.71 | PTGER4 (0.56) | ALDH1A1L3MBTL1 | |
| SCHEMBL15618424 | 0.71 | MAPK10 (0.53) | MEN1KMT2ARAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |