Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.54 |
| ▸ | POLB | P06746 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496461 | 0.84 | MEN1 (0.47) | MEN1KMT2APOLBALDH1A1BLM | |
| SCHEMBL3928131 | 0.81 | MAPT (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3928138 | 0.81 | MAPT (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL1496616 | 0.81 | MEN1 (0.58) | MEN1KMT2APOLBALDH1A1BLM | |
| SCHEMBL3966385 | 0.80 | HTT (0.60) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL13876933 | 0.78 | KMT2A (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3971120 | 0.77 | MAPT (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4969259 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL1496685 | 0.76 | MEN1 (0.67) | MEN1KMT2APOLBALDH1A1BLM | |
| SCHEMBL15618365 | 0.74 | DNMT1 (0.63) | MEN1KMT2APOLBALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |