SCHEMBL14964673

SCHEMBL14964673

CCCCCCCCC(N)(CCCCCCCC)CCCCCCCC.O=S(=O)(O)c1ccccc1

nearest known ligand 0.50

Known targets — ChEMBL curated mechanism

BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TDP1 Q9NUW8 1/20 0.41
S1PR3 Q99500 2/20 0.41
EPHX2 P34913 1/20 0.40
NAAA Q02083 3/20 0.40
PSIP1 O75475 1/20 0.39
PTGS2 P35354 1/20 0.39
TNNC1 P63316 5/20 0.39
SGPL1 O95470 1/20 0.39
S1PR4 O95977 1/20 0.39
S1PR1 P21453 1/20 0.39
GPR183 P32249 1/20 0.39
CERS2 Q96G23 1/20 0.39
S1PR5 Q9H228 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11466361 0.89 TSHR (0.48) TSHRSMN1; SMN2TDP1S1PR3EPHX2
Undecane SCHEMBL28277513 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
SCHEMBL29109146 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
Tetradecane SCHEMBL28309580 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
Decane SCHEMBL3917036 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
Octane SCHEMBL8591856 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
Heptane SCHEMBL18585529 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
SCHEMBL29277553 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
SCHEMBL29109142 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2
Nonane SCHEMBL28277510 0.87 SMN1; SMN2 (0.67) TSHRSMN1; SMN2TDP1S1PR3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780387-B1 POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE MITSUI CHEMICALS INC (JP) 2018-11-07 EP disclosed
US-9527948-B2 Polymerizable composition, optical article obtained therefrom and method for the production of said optical article MITSUI CHEMICALS, INC. (JP) 2016-12-27 US disclosed
US-20140327869-A1 POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE MITSUI CHEMICALS, INC. 2014-11-06 US disclosed
EP-2780387-A1 POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE Mitsui Chemicals, Inc. (JP) 2014-09-24 EP disclosed
WO-2013073194-A1 POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE MITSUI CHEMICALS, INC. (JP) 2013-05-23 WO disclosed