Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084898 | 0.85 | SLC6A2 (0.40) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL14965252 | 0.80 | SLC6A2 (0.32) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7301138 | 0.74 | SLC6A2 (0.36) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL28529030 | 0.73 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27840661 | 0.72 | SLC6A2 (0.35) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL21738844 | 0.72 | SLC6A2 (0.41) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4955381 | 0.71 | SLC6A3 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27921216 | 0.71 | SLC6A2 (0.35) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL8902551 | 0.69 | SLC6A2 (0.34) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL19140629 | 0.69 | SLC6A2 (0.38) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780344-A1 | THIENO [2, 3 - C]PYRAZOLES FOR USE AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072693-A1 | THIENO [2, 3 - C] PYRAZOLES FOR USE AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |