Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.36 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497110 | 0.83 | THRB (0.40) | THRBLMNA | |
| SCHEMBL22497980 | 0.79 | GNAO1 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12321134 | 0.78 | CPN1 (0.36) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL12321784 | 0.78 | CPN1 (0.36) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL16287489 | 0.78 | SHBG (0.44) | THRBLMNA | |
| Methyl Alcohol SCHEMBL27917454 | 0.78 | THRB (0.36) | THRBLMNA | |
| SCHEMBL20234883 | 0.78 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL11842539 | 0.76 | SHBG (0.48) | THRBLMNA | |
| SCHEMBL16287469 | 0.76 | SHBG (0.48) | THRBLMNA | |
| SCHEMBL28088063 | 0.76 | SHBG (0.48) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004862-A | Compound, pharmaceutical composition and application thereof | 山东大学 | 2025-05-16 | — | — | CN | claimed |
| CN-118027003-A | PROTAC compound, preparation method thereof and application of PROTAC compound as estrogen receptor degradation agent | 山东大学 | 2024-05-14 | — | — | CN | claimed |
| CN-120004862-A | Compound, pharmaceutical composition and application thereof | 山东大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-119462628-A | RAR PROTAC compound, pharmaceutical composition, preparation method and application | 湖北大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118027003-B | PROTAC compound, preparation method thereof and application of PROTAC compound as estrogen receptor degradation agent | 山东大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118146224-A | Nitrogen-containing tricyclic derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118027003-A | PROTAC compound, preparation method thereof and application of PROTAC compound as estrogen receptor degradation agent | 山东大学 | 2024-05-14 | — | — | CN | disclosed |
| EP-0503411-B1 | Substituted N-phenylpiperidines and medicaments thereof | BASF AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5296485-A | Substituted N-phenylpiperidines and drugs therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-22 | — | — | US | disclosed |