Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.68 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964850 | 1.00 | AKR1C1 (0.68) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL391072 | 0.90 | MAPT (0.61) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL14970313 | 0.86 | MAPT (0.57) | AKR1C1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL391070 | 0.83 | MAPT (0.58) | AKR1C1AKR1C3KMT2AALDH1A1MAPT | |
| SCHEMBL14970302 | 0.82 | KMT2A (0.55) | KMT2AALDH1A1MAPTLMNAGAA | |
| SCHEMBL181529 | 0.82 | AKR1C1 (1.00) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL39275 | 0.82 | AKR1C1 (1.00) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL290469 | 0.82 | AKR1C1 (1.00) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 | |
| SCHEMBL11154797 | 0.81 | MAPT (0.53) | KMT2AALDH1A1MAPTLMNAGAA | |
| SCHEMBL9125567 | 0.81 | AKR1C1 (0.75) | AKR1C1AKR1C2AKR1C3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |