Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964897 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2ALMNAGAA | |
| SCHEMBL14970299 | 0.87 | PTGS1 (0.68) | ALDH1A1MAPTKMT2ALMNAGAA | |
| SCHEMBL3577072 | 0.82 | HDAC3 (0.53) | KMT2AMEN1NQO2MTNR1AMTNR1B | |
| SCHEMBL3577074 | 0.82 | HDAC3 (0.53) | KMT2AMEN1NQO2MTNR1AMTNR1B | |
| SCHEMBL3577068 | 0.82 | HDAC3 (0.53) | KMT2AMEN1NQO2MTNR1AMTNR1B | |
| SCHEMBL9317348 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPTKMT2ALMNAGAA | |
| SCHEMBL14570726 | 0.77 | PTGS1 (0.65) | ALDH1A1MAPTKMT2ALMNAGAA | |
| SCHEMBL20400537 | 0.77 | CYP19A1 (0.48) | PTGS1PTGS2NQO2KDM4EGLA | |
| SCHEMBL25909565 | 0.77 | PTGS1 (0.65) | ALDH1A1MAPTKMT2ALMNAGAA | |
| SCHEMBL14621297 | 0.74 | NPC1 (0.50) | MAPTKMT2ARAB9AMEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |