Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | NQO2 | P16083 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964897 | 0.87 | ALDH1A1 (0.57) | PTGS1PTGS2NQO2ALDH1A1MAPT | |
| SCHEMBL14964896 | 0.87 | ALDH1A1 (0.57) | PTGS1PTGS2NQO2ALDH1A1MAPT | |
| SCHEMBL5606420 | 0.84 | ESR1 (0.62) | PTGS1PTGS2KMT2AESR1ESR2 | |
| SCHEMBL1226484 | 0.84 | ESR1 (0.62) | PTGS1PTGS2KMT2AESR1ESR2 | |
| SCHEMBL7912475 | 0.84 | ESR1 (0.62) | PTGS1PTGS2KMT2AESR1ESR2 | |
| SCHEMBL3988713 | 0.81 | ESR1 (0.82) | PTGS1PTGS2NQO2ESR1ESR2 | |
| SCHEMBL3988719 | 0.81 | ESR1 (0.82) | PTGS1PTGS2NQO2ESR1ESR2 | |
| SCHEMBL9622832 | 0.81 | ESR1 (0.82) | PTGS1PTGS2NQO2ESR1ESR2 | |
| SCHEMBL9317348 | 0.79 | ALDH1A1 (0.63) | PTGS1PTGS2ALDH1A1MAPTKMT2A | |
| SCHEMBL14570726 | 0.77 | PTGS1 (0.65) | PTGS1PTGS2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072390-A2 | STILBENE COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA TRANSMITTED ILLNESSES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-05-23 | — | — | WO | disclosed |