Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496616 | 0.83 | MEN1 (0.58) | ALDH1A1SMN1; SMN2L3MBTL1LMNAMEN1 | |
| SCHEMBL1496463 | 0.82 | HTT (0.67) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA | |
| SCHEMBL1496520 | 0.81 | MEN1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1LMNAMEN1 | |
| SCHEMBL29502867 | 0.80 | KMT2A (0.68) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA | |
| SCHEMBL18702851 | 0.80 | KMT2A (0.68) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA | |
| SCHEMBL11315787 | 0.77 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA | |
| SCHEMBL989785 | 0.75 | CES2 (0.58) | PKMRECQLMEN1KMT2AMAPT | |
| SCHEMBL3392821 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA | |
| SCHEMBL29529094 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA | |
| SCHEMBL3440916 | 0.74 | HCAR3 (0.57) | ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |