Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965132 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2 | |
| SCHEMBL14965285 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL16293998 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2 | |
| SCHEMBL14965245 | 0.80 | LMNA (0.49) | SMN1; SMN2 | |
| SCHEMBL14965026 | 0.79 | — | — | |
| SCHEMBL14965353 | 0.77 | POLB (0.60) | — | |
| SCHEMBL14965543 | 0.77 | POLB (0.60) | — | |
| SCHEMBL14965371 | 0.77 | POLB (0.60) | — | |
| SCHEMBL14965112 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL14965254 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |