Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965003 | 0.92 | ADORA3 (0.37) | — | |
| SCHEMBL14965152 | 0.89 | ADORA1 (0.37) | — | |
| SCHEMBL14965341 | 0.88 | ADORA1 (0.38) | — | |
| SCHEMBL14965320 | 0.83 | PTK2 (0.45) | — | |
| SCHEMBL14965245 | 0.81 | LMNA (0.49) | HTTKMT2A | |
| SCHEMBL14964954 | 0.79 | PTK2 (0.34) | — | |
| SCHEMBL14965271 | 0.77 | PTK2 (0.47) | — | |
| SCHEMBL14965308 | 0.75 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL14965062 | 0.75 | PTK2 (0.40) | — | |
| SCHEMBL14965080 | 0.73 | PTK2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |