Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965801 | 0.82 | TSHR (0.44) | MAPTSMN1; SMN2CYP3A4KDM4EMEN1 | |
| SCHEMBL14012789 | 0.81 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2LIN28ATDP1CYP1A2 | |
| SCHEMBL28498331 | 0.81 | SMN1; SMN2 (0.71) | MAPTSMN1; SMN2LIN28ATDP1CYP1A2 | |
| SCHEMBL14965536 | 0.81 | GBA1 (0.32) | — | |
| SCHEMBL8211629 | 0.79 | SMN1; SMN2 (0.75) | MAPTSMN1; SMN2LIN28ATDP1CYP1A2 | |
| SCHEMBL8211498 | 0.78 | SMN1; SMN2 (0.72) | MAPTSMN1; SMN2LIN28ATDP1CYP1A2 | |
| SCHEMBL6864610 | 0.78 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2LIN28ATDP1CYP1A2 | |
| SCHEMBL3739691 | 0.78 | SMN1; SMN2 (0.78) | MAPTSMN1; SMN2LIN28ATDP1CYP1A2 | |
| SCHEMBL14965993 | 0.78 | TSHR (0.44) | MAPTSMN1; SMN2CYP1A2KDM4ETSHR | |
| SCHEMBL14965745 | 0.77 | CHRNB2 (0.42) | MAPTSMN1; SMN2NR1H2NR1H3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |