Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969039 | 0.90 | TSHR (0.40) | TSHRMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL14966184 | 0.86 | CYP1A2 (0.39) | TSHRHSD17B10HTTALDH1A1KDM4E | |
| SCHEMBL14965745 | 0.86 | CHRNB2 (0.42) | TSHRHSD17B10HTTALDH1A1KDM4E | |
| SCHEMBL31482290 | 0.85 | TSHR (0.39) | TSHRHSD17B10MEN1KMT2AHTT | |
| SCHEMBL14965583 | 0.85 | TSHR (0.42) | TSHRHSD17B10MEN1KMT2AHTT | |
| SCHEMBL14965965 | 0.84 | MEN1 (0.43) | MEN1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL14965826 | 0.83 | MEN1 (0.60) | TSHRHSD17B10MEN1KMT2AHTT | |
| SCHEMBL14966345 | 0.82 | SLC6A4 (0.36) | TSHRMEN1KMT2AHTTACHE | |
| SCHEMBL15768271 | 0.82 | TSHR (0.35) | TSHRHSD17B10LMNAKDM4EBCHE | |
| SCHEMBL14965642 | 0.82 | HTT (0.37) | TSHRHSD17B10MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |