Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965801 | 0.90 | TSHR (0.44) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL16930000 | 0.89 | TSHR (0.36) | TSHRCALM1CAMKK2L3MBTL1HDAC3 | |
| SCHEMBL24570984 | 0.85 | MEN1 (0.35) | TSHRL3MBTL1ALDH1A1AKT1CNR2 | |
| SCHEMBL8720374 | 0.84 | HCRTR2 (0.41) | TSHRL3MBTL1ALDH1A1AKT1HTT | |
| SCHEMBL31111316 | 0.84 | DRD1 (0.36) | TSHRALDH1A1MAPK1HTTCYP1A2 | |
| SCHEMBL20564775 | 0.84 | DRD1 (0.36) | TSHRALDH1A1MAPK1HTTCYP1A2 | |
| SCHEMBL15768271 | 0.83 | TSHR (0.35) | TSHRCALM1CAMKK2L3MBTL1 | |
| SCHEMBL8721456 | 0.82 | LTA4H (0.42) | TSHRL3MBTL1ALDH1A1MAPK1MEN1 | |
| SCHEMBL31482290 | 0.78 | TSHR (0.39) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9185281 | 0.78 | IDO1 (0.42) | ALDH1A1MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |