Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965965 | 0.86 | MEN1 (0.43) | MEN1KMT2AIDO1KDM4EALDH1A1 | |
| SCHEMBL14966003 | 0.85 | CETP (0.50) | MEN1KMT2ATSHRHSD17B10KDM4E | |
| SCHEMBL14965583 | 0.84 | TSHR (0.42) | MEN1KMT2ATSHRHSD17B10IDO1 | |
| SCHEMBL14965801 | 0.83 | TSHR (0.44) | MEN1KMT2ATSHRHSD17B10KDM4E | |
| SCHEMBL4239892 | 0.83 | MEN1 (0.85) | MEN1KMT2ATSHRHSD17B10IDO1 | |
| SCHEMBL14965759 | 0.82 | MEP1B (0.48) | MEN1KMT2ATSHRHSD17B10KDM4E | |
| SCHEMBL14965745 | 0.78 | CHRNB2 (0.42) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL14971095 | 0.77 | MEN1 (0.60) | MEN1KMT2ATSHRHSD17B10KDM4E | |
| SCHEMBL14966345 | 0.77 | SLC6A4 (0.36) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL14966184 | 0.76 | CYP1A2 (0.39) | TSHRHSD17B10KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |