Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145730 | 0.78 | MAPT (0.41) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| Nitrogen SCHEMBL10975955 | 0.77 | MAPT (0.47) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL3034958 | 0.76 | L3MBTL1 (0.60) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL11361204 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL8408142 | 0.73 | GABRA1 (0.50) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL9545380 | 0.72 | KMT2A (0.58) | GABRA1GABRB2L3MBTL1HPGDKDM4E | |
| SCHEMBL16954554 | 0.72 | L3MBTL1 (0.43) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL12482259 | 0.72 | GABRA1 (0.45) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL9233724 | 0.72 | L3MBTL1 (0.43) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL293013 | 0.71 | SCN4A (0.52) | SCN5ACACNA1CKCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |