SCHEMBL8408142

SCHEMBL8408142

CCc1cccc(CC)c1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.50
GABRB2 P47870 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 1/20 0.40
ATM Q13315 1/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA14 Q9ULX7 1/20 0.40
PTGS2 P35354 2/20 0.39
HTR2A P28223 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22081624 0.89 GABRA1 (0.41) GABRA1GABRB2SMN1; SMN2KDM4EALDH1A1
SCHEMBL16955330 0.89 GABRA1 (0.46) GABRA1GABRB2SMN1; SMN2KDM4EALDH1A1
SCHEMBL464374 0.86 CA12 (0.54) SMN1; SMN2KDM4EALDH1A1MAPK1MAPT
SCHEMBL13344106 0.86 GABRA1 (0.43) GABRA1GABRB2SMN1; SMN2KDM4EALDH1A1
SCHEMBL12884485 0.85 GABRA1 (0.48) GABRA1GABRB2ALDH1A1HPGDADRA2A
SCHEMBL23536830 0.84 GABRA1 (0.52) GABRA1GABRB2SMN1; SMN2KDM4EALDH1A1
SCHEMBL12648278 0.84 SLC6A2 (0.43) GABRA1GABRB2ALDH1A1MAPK1MAPT
SCHEMBL300777 0.84 CA1 (0.53) GABRA1GABRB2KDM4EALDH1A1MAPK1
SCHEMBL16956553 0.84 GABRA1 (0.41) GABRA1GABRB2SMN1; SMN2KDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL7313508 0.84 CA12 (0.53) SMN1; SMN2KDM4EALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5475155-A Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation THE DOW CHEMICAL COMPANY (US) 1995-12-12 US claimed
WO-1995015301-A1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENES AND 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1995-06-08 WO claimed
US-11840601-B2 Composition of alkoxysilyl-functionalized epoxy resin and composite thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2023-12-12 US disclosed
EP-2616513-B1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECH CO (SA) 2019-11-06 EP disclosed
US-20170066789-A1 NOVEL EPOXY COMPOUND, MIXTURE, COMPOSITION, AND CURED PRODUCT COMPRISING SAME, METHOD FOR PREPARING SAME, AND USE THEREOF KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2017-03-09 US disclosed
CN-103097364-B Spiro-piperidine derivatives as S1P modulators ABBOTT HEALTHCARE PRODUCTS B.V. (NL) 2015-11-25 CN disclosed
CN-103097364-A Spiro-piperidine derivatives as S1P modulators ABBOTT HEALTHCARE PRODUCTS BV 2013-05-08 CN disclosed
US-20100112619-A1 LIGAND-CONTAINING MICELLES AND USES THEREOF GRAHAM RONALD J 2010-05-06 US disclosed
EP-0929506-A1 PROCESS FOR PREPARING STILBENE DIOLS THE DOW CHEMICAL COMPANY (US) 1999-07-21 EP disclosed
EP-0927149-A1 PROCESS FOR PREPARING AND RECOVERING 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE OR 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENE THE DOW CHEMICAL COMPANY (US) 1999-07-07 EP disclosed
WO-1998011043-A1 PROCESS FOR PREPARING STILBENE DIOLS THE DOW CHEMICAL COMPANY (US) 1998-03-19 WO disclosed
WO-1998011044-A1 PROCESS FOR PREPARING AND RECOVERING 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE OR 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENE THE DOW CHEMICAL COMPANY (US) 1998-03-19 WO disclosed
US-5723693-A Process for preparing and recovering 4,4'-dihydroxy-alpha-alkylstilbene or 4,4'-dihydroxy-alpha, alpha'dialkylstilbene THE DOW CHEMICAL COMPANY (US) 1998-03-03 US disclosed
US-5475155-A Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation THE DOW CHEMICAL COMPANY (US) 1995-12-12 US disclosed
WO-1995015301-A1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENES AND 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1995-06-08 WO disclosed
US-5414150-A Preparation of 4,4'-dihydroxy-alpha-alkylstilbenes and 4,4'-dihydroxy-alpha, alpha'-dialkylstilbenes THE DOW CHEMICAL COMPANY (US) 1995-05-09 US disclosed
EP-0173279-B1 2-(3,5-DIALKYL-4-HYDROXYPHENYL)INDOLE DERIVATIVES TEIKOKU HORMONE MFG. CO., LTD. (JP) 1989-08-23 EP disclosed
US-4695581-A LIPOXYGENASE INHIBITOR TEIKOKU HORMONE MFG. CO., LTD. (JP) 1987-09-22 US disclosed
EP-0173279-A1 2-(3,5-Dialkyl-4-hydroxyphenyl)indole derivatives TEIKOKU HORMONE MFG. CO., LTD. (JP) 1986-03-05 EP disclosed
US-4538003-A TREATMENT WITH MAGNESIUM OR ZINC ORGANOMETALLIC REAGENTS IN PRESENE OF A NICKEL BIDENTATE OR TRIDENTATE PHOSPHOROUS LIGAND E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170066789-A1 NOVEL EPOXY COMPOUND, MIXTURE, COMPOSITION, AND CURED PRODUCT COMPRISING SAME, METHOD FOR PREPARING SAME, AND USE THEREOF ESD, NOTUM, PFAS GABRA1 3432/4885GABRB2 4049/4885SMN1; SMN2 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.