Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393244 | 0.94 | LMNA (0.60) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL21393243 | 0.94 | LMNA (0.60) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL5949941 | 0.91 | LMNA (0.78) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL21393245 | 0.91 | LMNA (0.56) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL21393247 | 0.91 | LMNA (0.56) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL19757595 | 0.88 | HIF1A (0.55) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL2049440 | 0.87 | LMNA (0.52) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL2045144 | 0.85 | LMNA (0.50) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL4724285 | 0.84 | LMNA (0.53) | LMNACYP2C9TSHRKDM4EMAPT | |
| SCHEMBL28631164 | 0.83 | LMNA (0.67) | LMNATSHRPOLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114848640-B | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2023-04-07 | — | — | CN | claimed |
| CN-114848640-A | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2022-08-05 | — | — | CN | claimed |
| JP-3052838-A | — | — | None | — | — | JP | disclosed |
| CN-115385847-B | Polysubstituted diaryl compound, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2023-09-29 | — | — | CN | disclosed |
| CN-114848640-B | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2023-04-07 | — | — | CN | disclosed |
| CN-115385847-A | Polysubstituted diaryl compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-11-25 | — | — | CN | disclosed |
| CN-113387873-B | Substituted diaryl compound, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-20 | — | — | CN | disclosed |
| CN-114848640-A | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2022-08-05 | — | — | CN | disclosed |
| CN-109641831-B | Monomers, polymers, preparation method and use thereof | 东莞东阳光医疗智能器件研发有限公司 | 2021-09-10 | — | — | CN | disclosed |
| EP-3197482-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | Oxeia Biopharmaceuticals Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048488-A1 | METHODS OF TREATING TRAUMATIC BRAIN INJURY | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2016-03-31 | — | — | WO | disclosed |
| EP-1380342-A1 | COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-6147159-A | SUPPORT FOR USE IN SOLID PHASE SYNTHESIS COMPRISING A LINKER GROUP MADE BY HYDROSILATION OF A SOLID SUPPORT HAVING AN ALKENE EXTENDING THEREFROM WITH A DIHYDROGEN SILANE COMPOUND SUCH AS DIHALOSILANE, DIALKOXYSILANE, OR DIALKYLSILANE | ARGONAUT TECHNOLOGIES (US) | 2000-11-14 | — | — | US | disclosed |
| WO-1999017869-A2 | COMPOSITIONS FOR ORGANIC SYNTHESIS ON SOLID PHASE AND METHODS OF USING THE SAME | ARGONAUT TECHNOLOGIES (US) | 1999-04-15 | — | — | WO | disclosed |
| EP-0357409-B1 | Heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 1994-07-20 | — | — | EP | disclosed |
| JP-H0352838-A | PRODUCTION OF BETA-HYDROXYALKYL ARYL ETHER | MITSUI PETROCHEM IND LTD | 1991-03-07 | — | — | JP | disclosed |
| US-4994431-A | Containing colorless dye precursor, color developer and 1-alkoxy-phenoxy-2-aryloxypropane sensitizer; preservation stability, high sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0357409-A2 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4000315-A | Cyclopropane esters for the control of mites | ZOECON CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3957849-A | MITICIDES | ZOECON CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |