Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049440 | 0.98 | LMNA (0.52) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL1496625 | 0.85 | LMNA (0.67) | LMNACYP2C9TSHRPOLBKDM4E | |
| SCHEMBL970564 | 0.84 | LMNA (0.72) | LMNAKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL1001111 | 0.84 | LMNA (0.72) | LMNAKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL872625 | 0.82 | LMNA (0.75) | LMNAKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL8083747 | 0.82 | LMNA (0.46) | LMNAKMT2AADRB3TDP1ADRB2 | |
| SCHEMBL8081876 | 0.82 | LMNA (0.46) | LMNAKMT2AADRB3TDP1ADRB2 | |
| SCHEMBL2046633 | 0.82 | MAPT (0.47) | LMNATSHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL8081870 | 0.81 | LMNA (0.49) | LMNATSHRKMT2AALDH1A1MAPT | |
| SCHEMBL8083744 | 0.81 | LMNA (0.49) | LMNATSHRKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330464-A1 | PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE | FUJIFILM Corporation (JP) | 2011-06-08 | — | — | EP | disclosed |