SCHEMBL14966869

SCHEMBL14966869

CCCCCCOC(=O)C1OC12CCCC2

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.42
EPHX1 P07099 1/20 0.40
PRKCA P17252 4/20 0.39
TSHR P16473 2/20 0.39
PPARG P37231 3/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967101 0.98 NAAA (0.41) NAAAEPHX1PRKCATSHRPPARG
SCHEMBL14968079 0.98 NAAA (0.40) NAAAEPHX1PRKCATSHRPPARG
SCHEMBL14967315 0.97 ALDH1A1 (0.40) NAAAEPHX1PRKCATSHRPPARG
SCHEMBL16109750 0.97 NAAA (0.42) NAAAEPHX1PRKCATSHRPPARG
SCHEMBL16109629 0.95 NAAA (0.40) NAAAEPHX1PRKCATSHRPPARG
SCHEMBL14967755 0.94 ALDH1A1 (0.40) NAAAPRKCATSHRSMN1; SMN2HCAR2
SCHEMBL14967848 0.92 ALDH1A1 (0.40) NAAAPRKCATSHRSMN1; SMN2HCAR2
SCHEMBL16109828 0.91 ALDH1A1 (0.40) NAAAPRKCATSHRSMN1; SMN2HCAR2
SCHEMBL14967666 0.87 PPM1B (0.41) TSHRMAPK1HCAR2NPSR1
SCHEMBL14967850 0.86 ALDH1A1 (0.42) TSHRMAPK1HCAR2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed