SCHEMBL14967755

SCHEMBL14967755

CCCCOC(=O)C1OC12CCCC2

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.36
HPGD P15428 1/20 0.36
HCAR2 Q8TDS4 1/20 0.34
PRKCA P17252 2/20 0.33
NAAA Q02083 1/20 0.33
EPHX2 P34913 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PPP5C P53041 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967848 0.98 ALDH1A1 (0.40) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL16109828 0.97 ALDH1A1 (0.40) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL14968079 0.95 NAAA (0.40) ALDH1A1SMN1; SMN2TSHRHCAR2PRKCA
SCHEMBL14967315 0.94 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2TSHRPRKCANAAA
SCHEMBL14966869 0.94 NAAA (0.42) SMN1; SMN2TSHRHCAR2PRKCANAAA
SCHEMBL14967101 0.92 NAAA (0.41) ALDH1A1SMN1; SMN2TSHRPRKCANAAA
SCHEMBL16109629 0.92 NAAA (0.40) TSHRHCAR2PRKCANAAAEPHX2
SCHEMBL16109750 0.91 NAAA (0.42) TSHRHCAR2PRKCANAAA
SCHEMBL14967666 0.90 PPM1B (0.41) ALDH1A1LMNAPOLBMEN1KMT2A
SCHEMBL14967850 0.89 ALDH1A1 (0.42) ALDH1A1LMNAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed